Zencore Plus Recalled Because You Might Die

Activate descending slide whistle: Bodee LLC is recalling boner pill Zencore Plus because if you use it and take organic nitrates you might die. The interaction between the benzamidenafil and the organic nitrates can cause a “life-threatening” risk of a sudden and large drop in blood pressure, the FDA said in a press release, while noting that the probability of such an interaction occurring is unknown.

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  1. Saydur says:

    Aren’t there warnings to not take any of these types of pills with nitrates, due to a risk of exactly this happening? I’m surprised this wasn’t already known and documented as a warning.

    • Shaftoe says:

      @Saydur:
      Yeah I seem to recall that exact wording in the ads

    • Traveshamockery says:

      @Saydur: Unfortunately, just covering yourself via warnings isn’t enough to stop lawsuits.

      It’s also very possible (if not likely) that there are other major problems with the product, and this is just a cover to get it off the market without additional outrage.

  2. SkokieGuy says:

    This is the same warning and risk with Viagra, Levitra and Cialis (my friends have told me).

    I suspect that the product isn’t properly labelled with this warning and that was the cause of the recall.

    Their own site actually says one of the reasons to use their product is:
    You are worried about the adverse side effects of prescription drugs

    Pretty funny, since it now seems like their product has the exact same side effects as prescription drugs (i.e. potential death).

  3. Diet-Orange-Soda says:

    These are all basically blood-thinners right? A few shots of whiskey will do the same thing.

    • CubeRat says:

      @Diet-Orange-Soda:

      Is that so? Well, I know someone who is stopping by the liquor store after work. ;-)

    • WaywardSoul says:

      @Diet-Orange-Soda: Ummm, no and no.

    • ChuckECheese says:

      @Diet-Orange-Soda: I’m glad you’re not my doctor – lol. I know way too much about these drugs, as I have a chemist friend who worked on the development of Viagra as a boner drug in the early 90′s. Long before their FDA approval he was handing out Viagra tablets to friends in NYC clubs. These drugs were originally conceived as drugs to treat pulmonary hypertension and angina. They are still occasionally used for this reason.

      These substances work by releasing nitrous oxide into the bloodstream. This causes the relaxation and expansion of arteries throughout the body, including the sex organs, resulting in (increased) tumescence. There is a corresponding decrease in blood pressure as the arteries expand.

      There are other substances that do the same thing, such as amyl nitrite (poppers) and nitrous oxide gas (laughing gas). The fatal interaction comes with the additive effects of these substances, which can lead to a large decrease in blood pressure, such that one experiences heart failure.

      • Oranges w/ Cheese says:

        @ChuckECheese: So.. wait? Viagra is basically a temporary blood pressure downer? So.. by correlation can you then say people are having problems “performing” because they are fat and their arteries are clogged with crap?

        • rockasocky says:

          @Oranges w/ Cheese: Actually, yes, there is a correlation between being fat in the arteries and impotence. If I remember, some studies have shown that taking garlic (like, a LOT of it every day) lowers cholesterol and thus restores function to a man’s…er…man parts.

          @Diet-Orange-Soda: Alcohol is a “downer” so it actually makes things more difficult

          On a side note, I had to use “more difficult” instead of “harder” to avoid the pun.

      • npage148 says:

        @ChuckECheese:

        Actually they do not release nitrous oxide(N2O) in the blood stream. Viagra and the like prevent the degradation of cGMP (by inhibiting of PDE) which is produced by guanylyl cyclase which is activated by Nitric Oxide (NO). Organic nitrates (nitroglycerin, Isosorbide mononitrate, isosorbide dinitrate) are metabolized to release NO. So if you take organic nitrates you will have increase cGMP and taking viagra will prevent the breakdown of cGMP which will lead to WAY too much cGMP causing massive vasodilation dumping your blood pressure

        Nitrous oxide (laughing gas) has nothing to do with nitric oxide, huff it all you want and it won’t help. Amyl nitrite will.

        -Npage148
        Pharmacist and organic nitrate researcher

    • Jacob Morgan says:

      @Diet-Orange-Soda:
      Lechery, sir, it provokes, and unprovokes;
      it provokes the desire, but it takes
      away the performance: therefore, much drink
      may be said to be an equivocator with lechery:
      it makes him, and it mars him; it sets
      him on, and it takes him off; it persuades him,
      and disheartens him; makes him stand to, and
      not stand to; in conclusion, equivocates him
      in a sleep, and, giving him the lie, leaves him.

  4. SkokieGuy says:

  5. swissdietcoke says:

    I wonder if I’ll stop hearing the stupid commercials on clear channel radio now..

    “You’ll never believe how long you’re gonna last”

  6. SynMonger says:

    Oh god, I guess that means I shouldn’t be doing both of my favorite activities at once:

    Eating organic bacon and having sex. I’m just so sad now :(

  7. lalaland13 says:

    I just want some of these companies to go bankrupt and for these commercials to die. I saw a terrible one for something called Extenze or some such last night. Die in a fire.

    • SynMonger says:

      @lalaland13: Sounds like the one that uses those women who look like porn stars. The first time I saw that ad, I thought I was watching a dirty movie. I kept waiting for the action, and waiting, and waiting. I was so disappointed.

  8. SkokieGuy says:

    No stimulus package joke yet? Someone? Anyone?

  9. rbb says:

    Why do I feel dirty clicking on the “expand all” link in this thread to read all the replies?

  10. revmatty says:

    PSA (note this rant is slightly off topic as zencore isn’t really a supplement, but the general idea retains): If a supplement/herbal remedy/blah blah blah can have a positive effect on your body, it can also have a negative one. It angers me to no end when someone says “Oh, this new supplement I’m taking will help with my blood pressure/acne/halitosis/explosive diarrhea/etc and there’s no side effects like there are with prescription medications!”.

    Uh, no, genius. That is not the case. The difference is that supplements are 100% unregulated and they can be primarily composed of rat turds and the FDA can’t do anything about them. The supplements don’t have to include the disclaimers about side effects so people think they don’t exist.

    It is not possible to have a pill/salve/lotion/etc that *only* ever has positive effects and no possibility of side effects/negative effects. Anyone making that claim is a liar or an idiot. Or possibly both.

  11. FuryOfFirestorm says:

    Why does the FDA regulate prescription drugs, but not “herbal supplements”? They can be just as dangerous as medications, since anything can be put in a capsule and called a ‘natural remedy’. I bet the second the FDA starts cracking down on “homeopathic cures’, those damn Enzyte, Extenze, etc ads will disappear for fear of class action lawsuits.

  12. magic8ball says:

    Rrg. Reply is borked again. Ooh, but now preview is working. Weird.

    Anyway, @ChuckECheese: is a vasodilator and a blood thinner must have the same net effect, but are they actually the same thing?

  13. magic8ball says:

    And yet even with the preview I managed to screw it up. Should read “a vasodilator and a blood thinner must have the same net effect …”

    • ChuckECheese says:

      @magic8ball: No, because thin blood doesn’t make your bean snap, increased blood flow to the correct parts does. The effects of viagra and other nitrate donor meds are more than mere blood pressure decrease. They open your artery floodgates. And blood flow is what gets you pumpin’, so to speak. Plaque-coated arteries are constricted and can lead to decreased sexual function.

  14. MrsLopsided says:

    “while noting that the probability of such an interaction occurring is unknown.”

    I surmise that ‘unknown’ is somewhere between low and high.

  15. IvanaGabynoodle says:

    The FDA doesn’t regulate “supplements” or homeopathic stuff because Congress won’t let them. Supplements used to be regulated, and the manufacturers put together a successful campaign to change the law so they aren’t.

    The homeopathic stuff is explicitly not regulated, in the original law setting up the FDA. One of the congressmen at the time was a homeopathic physician and didn’t want non-homeopaths making rules about it. (That’s the friendly interpretation; the negative one would be that he suspected they would figure out that the stuff didn’t work and ban it as fraudulent.)

  16. savdavid says:

    You would go out smiling

  17. usa_gatekeeper says:

    Wow; I wonder how they’ll play this out in some upcoming CSI: Miami episode?!!!

  18. Alessar says:

    So, what we’re saying is this non-prescription item actually has the same chemical action as a prescription drug??

  19. npage148 says:

    Alessar: Yes, the OTC herbal supplement had a chemical in it that is very closely related to viagra and probably did the same thing. If you watch the FDA site they are constantly recalling OTC and herbals because they sneak prescription drugs in them and get caught. Weight loss products being especially common

  20. chilled says:

    I’ve tried Zencore…It’ll make you hard as long division…